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1 Red blood cell analyses showed that SOD activity and malondialdehyde (MDA) levels were significantly elevated and positively correlated with disease extent and activity, while CAT and glucose-6-phosphate dehydrogenase (G6PD) activities were significantly reducedfindings the authors described as supporting the hypothesis that widespread enzymatic deficiencies underpin vitiligo pathogenesis

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For patients with a history of treated and stable malignancies, tesamorelin therapy should be initiated only after careful evaluation of the potential benefit of treatment relative to the risk of re-activation of the underlying malignancy

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