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GLP-1 RAs exert an antihyperglycemic effect by enhancing pancreatic -cellmediated glucose-dependent insulin secretion, suppressing glucagon secretion, delaying gastric emptying, and reducing food intake in patients with T2D [6]
If a genuine plateau lasts several weeks despite consistent use, a provider will typically check a few things before deciding to increase the dose: If everything checks out and the plateau persists, moving to the next dose step is usually the next move
NAC deserves specific attention because it functions as a glutathione precursor rather than direct acetaldehyde scavenger
& Peskov, K
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