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10.1016/j.stem.2008.07.025 Cell Stem Cell 122 Terreros-RoncalJ.Moreno-JimenezE

Some potential concerns with long-term use of synthetic drugs include: Digestive discomfort (nausea, bloating, diarrhea) Possible nutrient absorption issues over time The need for ongoing injections or high-cost prescriptions Unknown effects from long-term artificial hormone stimulation Natural herbs and whole-food extracts work differentlythey support the bodys own GLP-1 production and related digestive functions rather than replacing or overriding them

A 2017 ACHI report found that medical and drug expenses increase along with the severity of obesity, with Arkansas health plans included in ACHIs review spending an average of 31% more on those who are obese than those who are not