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Benzyl alcohols preservative mechanism involves disruption of bacterial cell membrane lipid bilayer integrity and the aromatic alcohol partitions into bacterial membranes, increasing membrane fluidity and permeability, inhibiting electron transport chain function, and impairing membrane-dependent metabolic processes including nutrient transport and oxidative phosphorylation
freeze-thaw cycles promote aggregation
Use an insulated travel case with cold packs (not frozen solid, just chilled) to keep the vial between 36 and 46 degrees Fahrenheit
The proof is largely in vitro and animal research with minimal studies on people
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