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TRIM37 protects PGC development in a predominantly PGC-intrinsic manner Trim37 was expressed in both PGCs and SCs during PGC development (Supplementary information, Fig

At a pre-symptomatic stage, the deletion of Trkb in iSPNs leads to the upregulation of Gsto2 , increasing DA levels by controlling AA homeostasis and impacting energy metabolism, leading to progressive motor dysfunctions

the compound class is promising as a research platform for metabolic-disease biology and combinatorial strategies with diet or NAD precursor approaches

Analysis is performed by Freedom Diagnostics, a US-owned and operated laboratory named directly on each certificate and signed by its principal chemist