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Conclusions Significant weight regain occurred 8 weeks after discontinuation of AOMs and was sustained through 20 weeks

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Furthermore, targeting precision may be enhanced through various strategies, including high-throughput screening (HTS) to identify LNP formulations with specific organ tropism (184), cell membrane-coated nanoparticles (CMNPs) (185), and the design of triggerable release systems (186, 187), among others