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A lot is already known about topical depigmenting agents such as hydroquinone, glycolic acid, arbutin, kojic acid, vitamin C, vitamin E and niacinamide, all of which are readily available over-the-counter
Discontinue use and consult your healthcare provider if any adverse reactions occur
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One interesting theory Ive heard is that in people with a long history of alcohol-use disorder of heavy drinking that the blood-brain barrier becomes leakier, that its easier for different things to cross into the brain, and that, again, this may be one reason that GLP-1s perhaps are more effective in reducing substance use for people with alcohol-use disorder than other drugs
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