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Dose response curves of GLP-1 were generated and robust cAMP accumulation was observed for the GLP-1R (EC 50 = 9.0 pM) and GIPR/GLP-1R (1.3 nM)

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Tumour growth delay ( T C ) was calculated by subtracting the median time to reach evaluation size (750 mg) of the treated group by the median time to evaluation size of the control group