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Funding This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors
February 5, 2026
All 22 participants had previously been treated with a GLP-1 therapy for durations ranging from approximately 5 months to 5 years, with a mean total body weight loss of 24% while on therapy and a mean body weight of 80 kg 3 kg (SEM) at the time of intervention
Contact your healthcare provider immediately or seek emergency care if you experience: Severe, persistent abdominal pain that may radiate to the back Abdominal pain accompanied by nausea and vomiting that prevents you from keeping down food or liquids Fever along with severe abdominal pain If pancreatitis is suspected, discontinue tirzepatide immediately and do not restart if pancreatitis is confirmed
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