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The concomitant use of alcohol or central nervous system (CNS) depressant drugs with phentermine and topiramate extended-release capsules may potentiate CNS depression or other centrally mediated effects of these agents, such as dizziness, cognitive adverse reactions, drowsiness, light-headedness, impaired coordination, and somnolence

GLP-1 receptor agonist meds help regulate blood glucose by stimulating insulin secretion when blood sugar levels are high and reducing glucagon release to prevent spikes

This was significantly more than the placebo group, which only lost an average of 2.4% of their body weight

"These drugs aren't cures and don't change the underlying factors that cause weight gain ," he stresses