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PubMed Wedemeyer RS, Blume H
People assigned to receive higher doses started at 2 mg and increased the amount incrementally every four weeks until reaching the target dose (this step-up dosing is called titration)
difficulty breathing Signs of severe dehydration: dizziness, low urine output, rapid heartbeat Sudden severe upper right abdominal pain with fever or jaundice Use in Pregnancy and Breastfeeding Discontinue tirzepatide at least 2 months before a planned pregnancy due to its long half-life and potential for fetal harm
For some women, it can be particularly appealing if they are not candidates for estrogen therapy, do not want it, or are already using hormone therapy but still have skin or hair symptoms
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