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Imaging and trials show meaningful whole-body fat loss and a significant reduction in visceral fat, supporting metabolic improvements

2 Majority of patients were treated with standard of care 1,2,n,o Summary of medication at baseline (N=3533) 1,2 Select CV and CKD baseline characteristics (N=3533) 1,2 n At baseline patients in FLOW were receiving standard-of-care background therapy, including a maximum tolerated label dose of a RAAS-blocking agent including an ACE inhibitor or an ARB, unless such treatment was contraindicated or not tolerated

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So when a treatment plan helps lower systolic blood pressure, it may support better cardiometabolic health