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In this answer 3 sections The reason you started with intense every other day B12 shots and transitioned to a monthly schedule is a medical strategy called loading and maintenance. When you were first diagnosed, your bodys B12 stores were dangerously low

It is an advisory process related to whether nominated bulk drug substances may be appropriate for the 503A compounding framework

Surprisingly, studies have shown the benefits of vitamin B12 injections on people suffering from weight gain and obesity issues

The foundational obesity finding comes from Kraus and colleagues (Nature, 2014), who showed that knocking down NNMT protected mice against diet-induced obesity establishing NNMT as a metabolic target in the first place