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Exendin-4 administration did not modify S6K activity in the LH of lean and obese rats after four hours of re-feeding, whereas exendin-4 reduced S6K activity in the VMH of lean Zucker rats but not in their obese counterparts [83]

I was hopeful that it would be positive, but Im not surprised that its not, said Zaldy Tan, MD, MPH, director of the Bernard and Maxine Platzer Lynn Family Memory and Healthy Aging Program at Cedars-Sinai Medical Center

In addition to weight management, GLP-1 drugs like Wegovy and Zepbound also help in controlling high blood sugar in people with type 2 diabetes by stimulating insulin release from the pancreas

We want to be checking in with each dose titration, and I really believe the highest dose is not best dose necessarily for everyone. To minimize adverse events, Patnoe said, people with binge eating disorder and diabetes should eat small, frequent meals, consume bland and low-fat foods, eat high-protein meals, avoid lying down after eating and stay hydrated