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impaired fatty acid -oxidation metabolism and impaired branched-chain amino acid metabolism can lead to the accumulation of large amounts of acyl CoA

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Patients with baseline irritable bowel syndrome, inflammatory bowel disease, or prior gastrointestinal sensitivity may experience more pronounced symptoms

Training was conducted under a fixed ratio 1 (FR-1) schedule of reinforcement, where a single nose-poke in the active hole resulted in the delivery of a palatable pellet (BioServ, sweet dustless rodent pellets, F0021-Purified Casein-Based Formula, 45 mg), containing 276 g/kg of monosaccharides and 310 g/kg of sucrose