These include: Complete Blood Count (CBC) to check for better anemia Serum Vitamin B12 levels to make sure the dose is right Methylmalonic acid (MMA) and homocysteine levels to see how the body is reacting Reticulocyte count to see how the bone marrow is doing Clinical Improvement Markers We also watch for signs of improvement in how patients feel
iv) non-cardiac pathologies, with severe progression, which can generate arrhythmias such as hemorrhages, various neoplasms, hematological diseases, post-surgical conditions, infectious diseases, neuropsychiatric disorders, gout, hyperuricemia, renal insufficiency, hepatic, pulmonary failure and multiorgan failure
These symptoms typically occur during dose escalation and often diminish over time
Plan changes require active contact with the care team - they don't happen automatically