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GLP-1 drugs appear to have benefits beyond glucose and weight: reduced cardiovascular events, potential kidney protection, and even possible effects on neurodegenerative conditions and addiction
The mechanism may involve the upregulation of adenosine 5'-monophosphate-activated protein kinase (AMPK), peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC1-), and PPAR expression, as well as the upregulation of MCT1 and GLUT4 expression to improve metabolic transport (74)
These include Zepbound, Wegovy, Oral Wegovy, and Foundayo
Vrionedes, P.C
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