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FOXO4-DRI is a synthetic peptide designed as a retro-inverso analog of the transcription factor FOXO4, in which naturally occurring L-amino acids are substituted with their D-enantiomers
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Our findings demonstrated that the mouse intestinal pH was neutral to weakly alkaline from the duodenum to the rectum, and the amount of hydrogen contained in the large intestine was increased by administration of the Si-based agent (Fig
Development of an orally delivered GLP-1 receptor agonist through peptide engineering and drug delivery to treat chronic disease
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