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These symptoms may complicate the diagnosis and management of perioperative conditions that share similar clinical presentations

Metabolic acidosis, including diabetic ketoacidosis

In Vivo Assessment of Drug Interactions Effect of Sitagliptin on Other Drugs In clinical studies, as described below, sitagliptin did not meaningfully alter the pharmacokinetics of metformin, glyburide, simvastatin, rosiglitazone, warfarin, or oral contraceptives, providing in vivo evidence of a low propensity for causing drug interactions with substrates of CYP3A4, CYP2C8, CYP2C9, and organic cationic transporter (OCT)

Please consult your physician before beginning any treatment