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Esta translocacin se produce a travs de una serie de reacciones catalizadas por tres enzimas dependientes de carnitina que, juntos, representan el sistema de transporte de carnitina: El grupo acilo esterificado a CoA se transfiere a carnitina por carnitina-palmitoiltransferasa 1 (CPT-1) ubicado en la membrana mitocondrial externa