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The Batsis review answers this directly

It is suggested that there might be a link between the emergence of this tissue and the heightened activity of antioxidant enzymes

I think we really are at the doorstep of a new era in terms of how we are now going to be able to really effectively treat adolescent and pediatric patients with obesity. Sarah Armstrong, MD , professor of pediatrics and population health science at Duke University School of Medicine, echoed Foxs comments while adding that it is crucial for providers to think ahead when treating adolescents with obesity and to produce a gameplan for how to maintain weight loss

For instance, if youre experiencing severe nausea or gastrointestinal discomfort, they might lower your dose or switch you to a different GLP-1 medication