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07 Right upper-quadrant abdominal pain Gallstone risk increases with rapid weight loss

The triple-agonist hypothesis predicts that GIP receptor activation, by enhancing insulin secretion and improving glycemic control, will offset the hyperglycemic effects of glucagon receptor activation while preserving its energy-expenditure benefits

Because nausea, vomiting, constipation, and other digestive effects can occur, meal size and food choices may need to be adjusted with professional guidance