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GLP-1 treatments approved by the FDA come with a steep wholesale acquisition cost of over $12,000 per year

Additionally, semaglutide slows gastric emptying, prolonging the sensation of fullness and reducing the frequency of hunger signals

These medications, originally developed for diabetes management, improve multiple metabolic pathways implicated in metabolic dysfunction-associated steatotic liver disease (MASLD), formerly known as nonalcoholic fatty liver disease (NAFLD)

Long available for type 2 diabetes, the GLP-1 agonists expanded into weight management with approval of Saxenda (liraglutide) by the United States Food and Drug Administration (FDA) in 2014