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It promotes angiogenesis (formation of new blood vessels), supports collagen synthesis, and accelerates tissue regeneration
In proglucagon gene ( Gcg ) knockout mice, the GLP-1 receptor antagonist, exendin 9-39, led to impaired glucose tolerance when Gcg was reactivated in the pancreas, but not when intestinal Gcg was reactivated (115)
The answer is complex, but it is likely in large part due to the combination of its ubiquity in the body and the significant role it plays
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