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The fusion peptide demonstrated sleep-promoting effects, influenced neurotransmitter levels (5-HT, glutamate, dopamine, melatonin), and confirmed that the Tat cell-penetrating sequence was the more effective BBB carrier of two tested candidates establishing DSIP as a validated active scaffold for BBB-crossing fusion peptide sleep research and supporting the development of next-generation DSIP-based neuromodulatory tools

On September 27, 2020 (MEDLINE/PubMed), and October 30, 2020 (Scopus and Web of Science), databases were searched for ochronosis + hydroquinone by both authors to reduce risk basis

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