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This patchwork approach to coverage highlights a fundamental problem: patients are being forced to navigate an inconsistent and often opaque system just to access medically necessary care
These small molecule compounds mainly belong to iridoid glycosides, including geniposide, Shanzhiside methylester (SM), 8-O-acetyl-SM, morroniside, catalpol, genipin methyl ether and so on (18, 21)
The FDA could also request additional data after reviewing the NDA, which would push things further
Over time, you end up with a vial of fragments that used to be functional injectable peptide
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