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On the inspection of transcriptional level, it was unexpectedly to find that IGF-1 and EE significantly down-regulated MRF4 expression, since that down-regulation of MRF4 was reported in IGF-1 knockout mice 55
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10.1152/ajpregu.00128.2019 79 PriyadarshiniM.LaydenB
It is a GLP-1 receptor agonist, which means it mimics a natural gut hormone your body already releases after you eat
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