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Clinical evidence supports its use for chemotherapy-induced nausea, and many semaglutide users report benefit
GHRH 1-29 consists of the first 29 amino acids of the native GHRH peptide, and may potentially stimulate growth hormone production in pituitary gland cells, called somatotrophs
Patients typically report feeling fuller sooner during meals and experiencing reduced food cravings between meals, leading to decreased caloric intake without conscious restriction
The semaglutide and tirzepatide trials changed that expectation: Semaglutide 2.4 mg once weekly produced average weight loss around 15% at ~68 weeks in adults without diabetes, with a substantial fraction of participants losing 1520% of baseline weight
