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The accumulation of LCACs promotes mitochondrial failure by producing ROS [291], which block mitochondrial -oxidation by inhibiting redox-sensitive Slc25a20
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These include: nausea diarrhoea vomiting constipation abdominal discomfort or related gastrointestinal symptoms in some reports Published trial summaries have described these gastrointestinal events as dose-related and generally mild to moderate in severity
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