Consequently, active transporters located in the abluminal side of the BBB export AAs from the brain into the endothelial cell, to keep the lower concentration found in the extracellular fluid
doi:10.1017/S0029665107005563 Hedin C, Whelan K, Lindsay JO
Sacai H, Sakoori K, Konno K, Nagahama K, Suzuki H, Watanabe T, Watanabe M, Uesaka N, Kano M (2020) Autism spectrum disorder-like behavior caused by reduced excitatory synaptic transmission in pyramidal neurons of mouse prefrontal cortex
Published animal studies using BPC-157, including those extending across multiple weeks of daily administration, have not documented tumor formation or accelerated malignant growth as an observed outcome