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We thus performed OGTTs on Glp1r OB-hM3Dq WD mice after chemogenetic activation of OB Glp1r -expressing neurons with concurrent blockade of GABA A R in the PVN, using a local injection of the GABA A R antagonist bicuculline (Fig
The good news is that acid reflux on GLP-1 therapy is manageable and almost never requires stopping the medication
This provides convenient injection volumes (0.06mL for 2mg dose)
Discuss this with your healthcare provider or pharmacist, as they may recommend restarting at a lower dose to minimise side effects and gradually titrate back up to your previous dose, if appropriate
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