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Decreased collagen production, sIgE and Th2 cytokines IL-4, IL-5, and IL-13, and increased IFN- were observed in isolated splenocyte and lung cultures [100]

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For instance, a 12-month randomized controlled trial involving older adults (ages 60 to 81) demonstrated a 1.1-kilogram increase in fat-free mass with ibutamoren compared to placebo (14)

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