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In the shuttle, glutamate is converted to glutamine in astrocytes, and then exported to neuronal system A transporters, where it is converted to glutamate intracellularly by phosphate activated glutaminase (21)

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It has a better protective effect than ebselen, being several-fold more reactive in catalyzing the peroxide reaction

Storage checklist Lyophilized vials: -20 degrees C long-term, 2-8 degrees C short-term Reconstituted vials: 2-8 degrees C only, use within 30 days Never freeze reconstituted solution Protect from light at all stages Label every vial with reconstitution date and concentration Discard any vial exposed to room temperature for more than 12 hours Injection technique and site selection Cagrilintide is administered subcutaneously, meaning the needle goes into the fat layer just beneath the skin