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None of this erases the temporal, dose-related signalbut it does mean the signal should be read with caution and treated as hypothesis-generating
This allows for precise targeting of antigens like GLP-1R while minimizing the risk of nonspecific binding and side effects
Someone who slowly adds 20 pounds by their fifties, or gains weight after menopause as part of expected physiological change, may be on a very different footing from someone who has carried the disease since childhood
is supported by the Leicester NIHR Leicester Biomedical Research Centre and the University of Leicester
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