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Research has explored the compounds stability in gastric conditions compared to other peptides studied in that context, a meaningful trait since most peptides break down quickly in that environment
A deficiency in vitamin B12 may be found in persons with a diet limited in animal foods (such as vegans), or those with medical ailments affecting vitamin absorption
The design of these compounds mainly involves the replacement of the metal ion with rhodium, nickel, or zinc, or may have an inactive ligand attached, such as 4-ethylphenyl
The Cleveland Clinic notes that IV nutrient therapy may be appropriate in select clinical contexts when oral intake is limited or absorption is impaired
