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individuals with a BMI greater than 30 who have heart failure with preserved ejection fraction, uncontrolled hypertension or chronic kidney disease
To overcome the barriers and to improve the adherence, oral GLP-1 RAs were needed, but oral protein-based drug absorption is limited because of degradation in the stomach due to low pH, proteolytic enzyme activity, and limited permeability across the gastrointestinal (GI) epithelium
Further along, we discuss their FDA approval status and primary functions in managing type 2 diabetes
Future Outlook The market will expand rapidly with rising global cases of diabetes and obesity
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