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Key areas of research: NNMT Research Metabolic Research Body Composition Research Adipose Tissue Research Energy Expenditure Research Cellular Metabolism Research Glucose Regulation Research Obesity Research Methylation Pathway Research Cellular Energy Research References NNMT Regulates Cellular Metabolism: A Potential Therapeutic Target Discovery of 5-Amino-1MQ as a Potent NNMT Inhibitor The Role of NNMT in Obesity and Metabolic Regulation References are provided for research context only and do not constitute medical claims

Leloup et al., 2009

The study was supported by a National Institutes of Health (NIH) grant HD084422 to D.M.-R

MD analysis The mean binding free energies from all MD simulations are 12.7041 0.3243 kcal/mol for CME_a, 11.1474 0.8642 kcal/mol for CME_b, 15.4422 1.5895 kcal/mol for CME_c, and 39.3216 0.7125 kcal/mol for CME_d