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Of the 13 tested allozymes, eight exhibited minimal to no detectable sulfating activity (D46N, P54A, G57V, T58M, R132H, R259Q, G261V, and G261W), while the other five exhibited differential sulfating activity in comparison with the wild-type (P134L, D176N, R215H, S229T, and P330L)

55 Animal models to study the immunological consequences after disc herniations require surgical displacement of NP into immune surveilled tissue

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