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If it's a mild side effect, you know, like you have a little bit of reflux, you have a little, it's not major, but you can, you feel like a little off, then it is worth pushing because a lot of people find after four to six weeks that it starts to shift, that those side effects tend to dissipate

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Some research protocols combine both approaches for maximum metabolic correction

If a protocol calls for diluting the stock solution further, use a sterile, preservative-free diluent and prepare fresh working solutions rather than storing diluted aliquots for extended periods, since dilution can shorten the practical stability window