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In PsA, the phase 3b TOGETHER-PsA trial (NCT06588296) assesses the combined use of ixekizumab and tirzepatide in patients with active disease and concomitant overweight or obesity, while the phase 4 TOGETHER AMPLIFY-PsA study (NCT06864026) examines the effectiveness of adding tirzepatide to ixekizumab in clinical practice over 12 months

Interestingly, people who have used these medications have experienced significant weight loss around 12% to 17% of their body weight after using them for 48 weeks

Retatrutide is receiving attention because clinical trial coverage has reported substantial average weight loss in adults with obesity or overweight

BajicVPVan NesteCObradovicMZafirovicSRadakDBajicVBet alGlutathione redox homeostasis and its relation to cardiovascular disease