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ISGIO 2009, 2009
Avoiding aspartame when taking glutathione may improve the effectiveness of the antioxidant
Almost all antioxidant genes involved in ferroptosis, such as NADPH regeneration, glutathione-regulated and lipid peroxidation, may be potential therapeutic targets
Mutations in the SNCA gene promote -syn aggregation into oligomers or fibrils, which disrupt the ubiquitin-proteasome system and impair membrane binding by reducing its N-terminal -helical structure, leading to compromised membrane integrity and increased permeability (141, 142)
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