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Pro-inflammatory cytokines produced by adipose tissue support tumor-promoting intercellular crosstalk in the tumor microenvironment [14], thus enhancing tumor cell progression, angiogenesis, and invasion as essential requirements for metastasis [15]

The clients who see the most dramatic improvements are those who also focus on nutrition, exercise, sleep, and stress management

Russak EM, et al

Either way, considering the cost of these medications and the prevalence of both diabetes or obesity within a population, there is a potential for significant costs for the payers employers, employees or health insurance companies