Two estimands were employed: the trial product estimand, which evaluated treatment effects assuming perfect adherence to the assigned regimen, and the treatment policy estimand, which included all randomized participants regardless of adherence
Most "peptide weight loss" narratives fall into two buckets: Direct fat-loss claims: "It burns fat," "it speeds metabolism," or "it targets belly fat." Indirect support claims: "It helps recovery or inflammation, so you train more consistently." For BPC-157, the second bucket is more biologically plausiblebecause it's most commonly discussed in contexts like tissue repair, inflammation modulation, and gut comfort
A. V. Arutjunyan, I. G. Popovich, L. S. Kozina, and G. A. Ryzhak, Peptide Regulation of Ageing: From Experiment to Practice, Bentham Science Publishers Ltd., Feb. 2025. doi: 10.2174/0118746098346230250116065407
There's so many people on the opposite side of the aisle that it's a tough thing to navigate