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Estrogen drops less skin hydration, elasticity, and collagen Thinner, drier skin more prone to cracks, irritation, and flare-ups Weakened immune response increased skin reactivity Perimenopause also involves fluctuating progesterone, which can create more irregular cycles and skin changes

GLP-1 receptor agonists offer a solution to this problem

Baseline Demographics and Medication Profiles A total of 125 youth were included (median age 14.83 years), with 113 on metformin and 12 on GLP-1RA therapy

Elliott Lewis, a psychiatrist and obesity medicine specialist, frames it this way: If we truly understand that metabolic and mental health systems are inseparable, then psychiatrists being involved in metabolic treatment makes complete sense. Youre not stepping outside your lane youre addressing the whole patient