(PubMed) Safety depends heavily on product purity, sterile technique, dosing, and supervision by licensed medical professionals
We have previously shown that in the case of l-arginine, the direct sensor was a periplasmic l-arginine binding protein, ArtI, which activates the diguanylate cyclase, YedQ (also called STM1987)
Indeed, a large number of previous studies examining the status of antioxidants in mucosa from patients and experimental animal models of colitis have reported a decrease in the levels of antioxidants, including that of GSH (Buffinton and Doe, 1995
IV nutrient therapy may help manage some of these effects: Fatigue : B vitamins, magnesium, and amino acids delivered intravenously can help address fatigue, which affects up to 90% of cancer patients