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Because collagen acts as the structure that holds everything up, a lack of it causes skin to sag or wrinkle
Green RM, Graham M, ODonovan MR, Chipman JK, Hodges NJ
Results Iron overload in CD11c + myeloid cells exacerbates APAP-induced liver damage To explore the roles of iron in CD11c + myeloid cells during liver inflammation, we crossed Fbxl5 F/F mice harboring floxed Fbxl5 alleles with Cd11c (also known as Itgax ) - Cre transgenic mice (expressing Cre recombinase under the regulation of the Cd11c promoter)
To test a general applicability of this mechanistic model, we confirmed our findings for the non-related enzyme PfGrx from the malaria parasite Plasmodium falciparum 18,33
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